Rafscience.com is an educational resource for medical professionals interested in learning more about the role of the RAF kinase cell signaling pathway in hepatocellular carcinoma (HCC). Activated RAS "turns on" the serine threonine-protein kinase known as RAF kinase, which then activates downstream effectors involved in many aspects of tumorigenesis—from cell immortalization to angiogenesis and drug resistance. Keep visiting this site as new knowledge emerges on the role of RAF kinase in tumorigenesis.
Hepatitis viruses are responsible for over 80% of HCC cases worldwide.